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Children With Partial IgA Deficiency
Clinical Pediatrics, 01/17/2012
Shakkottai A et al. – Partial IgA deficiency appears to be associated with rheumatic diseases and complaints of joint pain, joint swelling, and morning stiffness. A larger study is needed to confirm these results.
Methods- The authors conducted a retrospective chart review of 13 patients with partial IgA deficiency followed at the pediatric rheumatology clinic at Robert Wood Johnson Medical School.
- They looked for the presence of rashes, joint pain, joint swelling, and morning stiffness.
- The authors also examined charts for a history of frequent infections, allergies, and the presence of elevated antinuclear antibody.
- Eleven out of the 13 patients complained of joint pain, joint swelling, or morning stiffness.
- Six patients carried a diagnosis of a definitive rheumatic disease.
- Four patients suffered from frequent infections and 2 patients reported allergies.