Defining Risk Factors for Red Man Syndrome in Children and Adults
The Pediatric Infectious Disease Journal, 05/04/2012Myers AL et al.
Red man syndrome (RMS) is a common adverse event in children receiving vancomycin. Identified risk factors are Caucasian ethnicity, age> 2 years, previous RMS history, vancomycin dose > 10 mg/kg, vancomycin concentration > 5 mg/mL and antecedent antihistamine use. Known genetic variants in histamine metabolism or receptors do not appear to be substantial contributors to risk of RMS.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.