No detectable beneficial systemic immunomodulatory effects of a specific synbiotic mixture in infants with atopic dermatitis

Clinical & Experimental Allergy, 04/18/2012

This synbiotic mixture has no detectable effect on plasma levels of the analysed atopic disease markers, ex vivo cytokine production and circulating regulatory T cell percentage in infants with atopic dermatitis, besides down–regulation of IL–12 production in egg– and peanut–stimulated peripheral blood mononuclear cells (PBMCs). These results do not support the use of this synbiotic in clinical practice.

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