Comparison of distress and pain in infants randomized to groups receiving standard versus multiple immunizations
Infant Behavior and Development, 06/10/2010Hanson D et al.
Simultaneous injections appeared to be effective in reducing pain behavior responses in infants receiving their 4–month immunizations. Longitudinal studies could determine whether reduced exposure to pain in infancy, through simultaneous immunization injections, could contribute to a reduction in sensitivity to pain and physiologic stress responses.
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