Zappitelli M et al. – The authors summarize why neonates are predisposed to drug nephrotoxicity, review the mechanisms and clinical picture of the most common nephrotoxic medications used in neonates (aminoglycosides, vancomycin, amphotericin B, acyclovir, nonsteroidal anti–inflammatory drugs, and radiocontrast agents), and discuss the roles of angiotensin–converting enzyme inhibitors and diuretics in nephrotoxicity. [more...]