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Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury
Intensive Care Medicine, 10/28/09
Sapru A et al. – Higher PAI–1 levels are associated with increased mortality and fewer ventilator–free days among pediatric patients with ALI. These findings suggest that impaired fibrinolysis may play a role in the pathogenesis of ALI in pediatric patients and suggest that PAI–1 may serve as a useful biomarker of prognosis in patients with ALI.
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