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See Latest ArticlesIn pursuit of prognostic factors in children with pilocytic astrocytomas
Child's Nervous System, 10/29/09
Becker AP et al. – Aside from GTR, no other clinical, histopathological, or immunohistochemical features were found to be related to the prognosis. The authors postulate that strict follow–up is recommended if piloA is associated with high mitotic activity/Ki67–LI, or if GTR cannot be achieved at surgery. Tumor recurrence or progression of the residual lesion should be strictly observed. In some aspects, childhood piloA remains an enigmatic tumor.
Ricardo Santos de Oliveira, 10/29/09
| Aside gross tumor resection no clinical or microscopic factors were significantly related to patients’ outcome. In some aspects, pilocytic astrocytoma in children remains an enigmatic tumor. Further series with molecular studies focused on the genetic alterations can offer a better comprehension of the pathobiology of these tumors and are highly expected. |
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