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Prevention of Hyponatremia during Maintenance Intravenous Fluid Administration: A Prospective Randomized Study of Fluid Type versus Fluid Rate
The Journal of Pediatrics, 10/13/09
Neville KA et al. – On multiple linear regression analysis, fluid type, not rate determined risk of hyponatremia. Two children on 100% developed SIADH. Fourteen on 50% maintenance were assessed as dehydrated. Dextrose content was increased in 18 for hypoglycemia or ketosis. The risk of hyponatremia was decreased by isotonic saline solution but not fluid restriction.
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