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Liu J et al. – The results showed: the serum concentrations of IL–1 beta, IL–8 and TNF–alpha in umbilical and peripheral blood were significantly higher in HIE patients than control groups; the umbilical blood concentrations of IL–1 beta exhibited the best positive correlation with HIE grades, when compared with IL–8 and TNF–alpha ; and abnormal neurological outcomes at 6 and 12 months of age were best predicted by umbilical levels of IL–1 beta.

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