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Obese Children with Low Birth Weight Demonstrate Impaired -Cell Function during Oral Glucose Tolerance Test
Journal of Clinical Endocrinology and Metabolism, 10/15/09
Brufani C et al. – SGA obese children fail to adequately compensate for their reduced insulin sensitivity, manifesting deficit in early insulin response and reduced disposition index that results in higher glucose AUC. Thus, SGA obese children show adverse metabolic outcomes compared to AGAs and LGAs.
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