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Acute silent cerebral infarction in children with sickle cell anemia
Pediatric Blood & Cancer, 10/09/09
Dowling MM et al. – The authors report acute SCI in seven children with HbSS who had areas of restricted diffusion on MRI without persistent focal neurologic deficits. Four had acute SCI identified following acute anemic events. This observations suggest that SCI are detectible in the acute phase, present with subtle neurologic symptoms, result in permanent neurologic injury, and may be caused by acute anemic events.
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