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Zhao X et al. – The authors found a statistically significant relationship between the percent of cyclinD1–positive cells and p16–positive cells in the tumors and clinical outcome, with higher levels of cyclinD1 and lower levels of p16 correlating with a worse prognosis. CyclinD1 and p16 may be independent biomarkers for clinical prognosis in MB. A combined detection of cyclinD1+/p16? expression may benefit us in prediction of a poor survival of MB.


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