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Garzon DL et al. – Childhood depression is probably overlooked more than it is diagnosed and treated, and PCPs are often the first to identify the warning signs. Untreated childhood depression can adversely affect growth and development, increase the risk for substance abuse and other dangerous behaviors, and result in death by suicide. All PCPs should be able to recognize signs of depression and institute a basic plan that provides for safety, a therapeutic relationship, and ongoing social support for the patient. Referral to mental–health specialists is indicated for professional psychotherapy and must be considered if the PCP is uncertain about how to proceed once initial treatment fails or if the child's situation is potentially life–threatening. By virtue of an established relationship with children and their parents and the extensive background knowledge of the patient, PCPs can bring about positive outcomes for depressed children and adolescents.

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