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Secular Variation in United States Rotavirus Disease Rates and Serotypes: Implications for Assessing the Rotavirus Vaccination Program
The Pediatric Infectious Disease Journal, 10/05/09

Payne DC et al. – During the 2006 and 2007 rotavirus seasons, with only limited vaccine use, remarkable variability was observed in the population–based rates of severe rotavirus and in the rotavirus serotypes across the 3 sites. This natural secular variability in rotavirus disease must be considered in the assessment of the impact of vaccine on disease rates and rotavirus serotypes.

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