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Shin SH et al. – The enteroviral infection may be a major cause of febrile episodes in infants younger than three months. If UTI could be excluded, the presence of CRP levels >=1.87 mg/dL and fevers of >=38.9 degrees C can be used as criteria to rule out SBI in these infants.


Exclusive Author Commentary
Chang Won Choi, 10/05/09

The shared peak season (June and July) for the visits of febrile infants, febrile illness without a documented cause (FISDC), aseptic meningitis and positive CSF enterovirus PCR and the high frequency of positive CSF enterovirus PCR in FISDC and aseptic meningitis cases suggest that enteroviral infection may be a major cause of febrile episodes in these infants and that FISDC and aseptic meningitis may be parts of a continuum of enteroviral infection rather than separate diseases.


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