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Gabrovsky A et al. – The authors report a patient with hemoglobin SC disease and prolonged, life–threatening hemorrhage from papillary necrosis successfully treated with oral, low–dose epsilon aminocaproic acid. Although further study is warranted, this case illustrates the need to consider EACA in the conservative management of renal papillary necrosis and significant hemorrhage in sickle cell hemoglobinopathies.

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