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See Latest ArticlesCushing disease as possible cause of persistent growth failure despite growth hormone therapy in a small for gestational age male
Pituitary, 09/25/09
Heneghan M et al. – The authors report the case of an 11–year–old Caucasian male who developed early adrenarche, hypertension and insulin resistance on GH therapy for SGA and profound short stature. The patient’s diagnosis of Cushing’s disease was complicated by his past history of poor growth since birth and history of SGA. The signs of Cushing’s disease did not overtly appear until GH therapy was initiated to help treat severe short stature. It is possible that the metabolic effects of GH therapy unmasked the presence of underlying Cushing’s disease.
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