Pediatrics Medical News about IGF1 Mutation

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Use of Antiemetic Agents in Acute Gastroenteritis

3. 2008 Exclusive Survey—Earnings: Good news for primary care income

4. Medicare pay-for-reporting effort draws fire from frustrated doctors

5. Debunking Myths in the US Healthcare System

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Partial Primary Deficiency of Insulin-Like Growth Factor (IGF)-I Activity Associated with IGF1 Mutation Demonstrates Its Critical Role in Growth and Brain Development
Journal of Clinical Endocrinology and Metabolism, 10/12/09

Netchine I et al. – This first report of mild deficiency of IGF–I activity demonstrates that the integrity of IGF–I signaling is important for normal growth and brain development. Molecular defects leading to partial loss of IGF–I activity may not be uncommon in patients born small for gestational age. The characterization of this complex phenotype and identification of such molecular defects have therapeutic implications, particularly now that, in addition to GH, recombinant IGF–I is available for clinical use.

<< Previous
Identification and Functional Studies of Two New Dual-Oxidase 2...

Next >>
Gender-Specific Prevalences of Fatty Liver in Obese Children and...