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Kudo K et al. – Langerhans cell histiocytosis (LCH) that is refractory to conventional chemotherapy has a poor outcome. Hematopoietic stem cell transplanta tion (SCT) is a promising approach for refractory LCH because of its immunomodulatory effect. The results indicate that SCT is promising as a salvage approach for children with refractory LCH.


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