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Zhang L et al. – Wnt1 and beta–catenin expressed in SH–SY5Y cells. Knockdown of endogenous wnt1 expression could result in cell death and inhibit cell growth. From this study, authors suggest that the activated embryonal development–related wnt1/ beta–catenin pathway might take part in the oncogenesis and growth of neural crest–derived neuroblastoma.


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