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See Latest ArticlesInvolvement of tryptophan hydroxylase 2 (TPH2) gene polymorphisms in susceptibility to coronary artery lesions in Korean children with Kawasaki disease
European Journal of Pediatrics, 10/12/09
Park SW et al. – The genetic data, SNPStats, SNPAnalyzer, and Helixtree programs were used. The genotype analysis of rs7305115 and rs4290270 showed no significant differences between KD and control groups. However, authors found a statistically significant association between the two SNPs and the development of CALs in KD. The minor homozygous genotype of each SNP showed increased susceptibility to risk of CALs in KD patients. These results suggest that TPH2 may be associated with the development of KD with CALs in Korean children.
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