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See Latest ArticlesViolation of the ISNT Rule in Nonglaucomatous Pediatric Optic Disc Cupping
Investigative Ophthalmology and Visual Science, 09/10/09
Pogrebniak AE et al. – Violation of the ISNT rule occurs with greater frequency in the pediatric population with large optic disc cups of nonglaucomatous origin, compared to the pediatric population with normal optic discs. In discs with small cups, neuroretinal rim width conforms to the overall oval shape of the disc, which is usually greatest in vertical dimension, whereas discs with large cups possess greater variability of relative neuroretinal rim width around the disc, greater relative vertical cup/disc ratio versus horizontal cup/disc ratio, and lower predictability of the ISNT rule.
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