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Acquired somatic mutations in the microsatellite DNA, in children with bronchial asthma
Pediatric Pulmonology, 09/04/09
Thomou C et al. – This results showed that genetic instability in the MS DNA, is present in asthmatic children, but to less extent than in adult asthmatics from previous studies. These findings may support the hypothesis that somatic mutations may be early acquired in the natural course of asthma and could represent another contributor to the molecular pathogenesis of the disease.
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