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See Latest ArticlesEvaluation of C677T and A1298C polymorphisms of the MTHFR gene as maternal risk factors for Down syndrome and congenital heart defects
American Journal of Medical Genetics, 09/08/09
Carneiro Brandalize AP et al. – Maternal 677T allele may be associated with an increased occurrence of CHD in children with DS and the authors anticipate that women who carry this polymorphism would benefit from periconceptional folic acid supplementation.
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