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Gerday E et al. – Platelet (PLT) transfusions can bestow significant benefits but they also carry risks. This study sought a safe means of reducing PLT transfusions to neonatal intensive care unit (NICU) patients with thrombocytopenia by comparing two transfusion guidelines, one based on PLT count and the other on PLT mass (PLT count times mean PLT volume). The use of PLT mass–based NICU transfusion guidelines was associated with fewer PLT transfusions and no recognized increase in hemorrhagic problems.

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