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PTGDR is not a major candidate gene for asthma and atopy in Chinese children
Pediatric Allergy and Immunology, 08/31/09
Leung TF et al. – Asthma diagnosis, atopy and aeroallergen sensitization did not differ among children with different PTGDR genotypes. Linear regression showed weakly significant associations between T–197C and G1044A of PTGDR and spirometric variables. PTGDR haplotypes were not associated with asthma and atopy phenotypes. The results do not support PTGDR to be a major candidate gene for asthma traits in Chinese children.
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