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No child left behind: Enrolling children and adults simultaneously in critical care randomized trials
Critical Care Medicine, 08/28/09

Halpern SD et al. – The current standard of testing critical care interventions in adults before children rests on tenuous ethical arguments and is entrenched by the methodologic and logistic barriers encountered with alternative approaches. However, these barriers will frequently be surmountable. We therefore propose that the default paradigm be changed such that interventions are examined routinely in critically ill children and adults simultaneously unless unique reasons exist to the contrary.

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