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See Latest ArticlesSUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation
Journal of Immunology, 08/20/09
Luciani A et al. – TG2 may function as a link between oxidative stress and inflammation by driving the decision as to whether a protein should undergo SUMO–mediated regulation or degradation. Targeting TG2–SUMO interactions might represent a new option to control disease evolution in CF patients as well as in other chronic inflammatory diseases, neurodegenerative pathologies, and cancer.
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