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Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility
Diabetes/Metabolism Research and Reviews, 07/29/09
Knip M et al. – Among young IAA–positive children with HLA–conferred disease susceptibility IAA affinity failed to distinguish rapid progressors from slowly or non–progressing subjects. In relation to IAA affinity, no maturation of the humoral immune response was observed over time from seroconversion to diagnosis.
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