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Neck nodule and thyroid cancer in young without radiation exposure history
Pediatric Surgery International, 08/05/09

Liu FH et al. – In the study population, 20.1% of the neck masses were malignant. Except in cases of follicular thyroid neoplasm, neck ultrasonography with FNAC could effectively identify the thyroid or non–thyroid origin of these masses with high–diagnostic accuracy.

Exclusive Author Commentary
Jen-Der Lin, 08/08/09

We emphasized this article on a retrospective review of 234 young patients without history of radiation exposure with an anterior neck masses found, who underwent preoperative ultrasonographic examination and fine-needle aspiration cytology (FNAC). Thus far, we do not have enough information about young patients with a neck mass that has surgically been confirmed to be non-thyroid in origin. Malignant thyroid nodules were identified in 47 cases (20.1%); 187 (79.9%) were surgically confirmed to be benign lesions, including benign thyroid nodular hyperplasia, thyroid follicular adenoma, thyroiditis, extra-thyroid masses and parathyroid enlargement. There were 207 neck nodules arising from the thyroid; 22 cases of neck nodules to be non-thyroid in origin, including those arising from developing cyst, soft tissue tumor, or those that were lymphatic in origin; 5 nodules indicated parathyroid enlargement (3 parathyroid adenomas, 1 parathyroid hyperplasia, and 1 parathyroid atypical adenoma). Neck ultrasonography and FNAC can effectively differentiate between tumors of thyroid and non-thyroid origins with a high diagnostic accuracy.

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