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Prolonged Neutropenia after Irinotecan-based Chemotherapy in a Child with polymorphisms of UGT1A1 and SLCO1B1
BMJ - Archives of Diseases in Childhood, 07/22/09
Sakaguchi S et al. – The authors report an 11 year old female with severe and prolonged neutropenia after irinotecan–based chemotherapy. The patient’s genotyping revealed polymorphisms in both UGT1A1 and SLCO1B1.
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