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The effect of bosentan in patients with a failing Fontan circulation
Cardiology in the Young, 07/17/09
Ovaert C et al. – The study failed to show significant improvement after 3 months of treatment with bosentan in a small group of patients with failing Fontan circulations. Some individuals, nonetheless, did improve. When planning larger trials, it would be better to identify those patients who might potentially benefit from the treatment prior to commencing the trial.
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