Pediatrics Medical News about tubular proteinuria

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Decreased renal uptake of 99mTc-DMSA in patients with tubular proteinuria
Pediatric Nephrology, 07/16/09

Lee BH et al. - Patients with various proximal tubular disorders show markedly decreased renal DMSA uptake, even when there is normal creatinine clearance. The results strongly suggest that DMSA is filtered in the glomeruli and subsequently undergoes megalin- and cubilin-mediated endocytosis in the proximal tubules.

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