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Fluconazole Dosing for the Prevention or Treatment of Invasive Candidiasis in Young Infants
The Pediatric Infectious Disease Journal, 07/15/09
Wade KC et al. - A therapeutic concentration of fluconazole in premature infants with invasive candidiasis requires dosing substantially greater than commonly recommended in most reference texts. To prevent invasive candidiasis, twice weekly prophylaxis regimens can provide adequate exposure when unit specific MICs are taken into account.
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