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See Latest ArticlesRapid discontinuation of corticosteroids in pediatric renal transplantation
Pediatric Transplantation, 07/13/09
Barletta GM et al. - There was 100% patient and rejection-free graft survival at 27 months post-transplantation; 47% underwent renal transplant biopsy secondary to acute rise in serum creatinine with or without worsening hypertension. All biopsies had no evidence of acute rejection; 62.5% had findings consistent with tacrolimus toxicity. Renal transplantation utilizing a rapid discontinuation of corticosteroid protocol in pediatric patients appears to be safe and effective, without increasing the risk of acute rejection or graft loss.
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