Your Article Summary
See Latest ArticlesProspective evaluation of a shortened regimen of treatment for acute osteomyelitis and septic arthritis in children
Journal of Pediatric Orthopaedics , 07/01/09
Jagodzinski NA et al. – Study reports that a shortened course of intravenous and oral antibiotic therapy is effective in the management of acute uncomplicated bone and joint sepsis in children.
Methods- Aim was to investigate if children could be safely treated with 3 days of high-dose iv therapy followed by 3 wks of oral therapy in uncomplicated bone and joint infections
- Inclusion criteria for entry into the database were:
- Children ≤16 years of age who had no underlying disease or medical therapy predisposing to infection, and
- Who had symptoms for less than 14 days before presentation
- They were all started on iv antibiotics and a predetermined treatment algorithm was followed
- All pts with septic arthritis also underwent joint washout
- Pts were converted to oral antibiotics once they improved clinically and hematologically
- Regular outpatient f/u continued for 1 yr with blood tests and X-rays
- 70 consecutive, eligible children aged 2 wks-14 yrs
- Staphylococci were the only organisms isolated in cases of osteomyelitis
- Whereas Streptococcal infection was more prevalent in pts with septic arthritis
- 59% of children could be converted to oral therapy after 3 days of iv therapy and 86% after 5 days
- Median duration of inpatient stay was 5 days
- 3 wks of oral therapy was appropriate for those pts who received 5 days or less iv treatment
- Temperature and CRP were the best quantitative means of monitoring response to therapy
- All pts were clinically, hematologically, and radiologically normal before discharge 1 yr post-presentation
Related Articles
Septic Arthritis in Adults with Sickle Cell Disease Often is Associated with Osteomyelitis or Osteonecrosis
Clinical Orthopedics and Related Research, 11/11/09
Relevance Score: 68%
Septic arthritis of the knee joint secondary to adjacent chronic osteomyelitis of the femur in an adult
Knee Surgery, Sports Traumatology, Arthroscopy, 11/11/09
Relevance Score: 67%
Mycobacterium Kansasii Causing Septic Arthritis and Osteomyelitis in A Child
The Pediatric Infectious Disease Journal, 11/05/09
Relevance Score: 67%
Septic arthritis due to Roseomonas gilardii in an immunocompetent adolescent
Journal of Medical Microbiology, 10/21/09
Relevance Score: 67%
Extended scope of autologous chondrocyte implantation for osteochondral injuries following septic arthritis: A case report
The Knee, 10/01/09
Relevance Score: 67%
Today in Pediatric Emergencies...keeping you current
Receive free subspecialty "5-minute updates" via email
Intestinal Ischemia-reperfusion Injury Causes Activation of Bone Marrow-derived Progenitor Cells
European Journal of Pediatric Surgery, 12/19/09
Paediatric Blunt Liver Trauma in a Dutch Level 1 Trauma Center
European Journal of Pediatric Surgery, 12/19/09
Severe Micrognathia: Indications for EXIT-to-Airway
Fetal Diagnosis and Therapy, 12/19/09
Today in Pediatric Ortho/Rheum...keeping you current
Receive free subspecialty "5-minute updates" via email
School Playground Surfacing and Arm Fractures in Children: A Cluster Randomized Trial Comparing Sand to Wood Chip Surfaces
PLoS Medicine, 12/17/09
Do infections trigger juvenile idiopathic arthritis
Rheumatology International, 12/16/09
The role of exercise therapy in the management of juvenile idiopathic arthritis
Current Opinion in Rheumatology, 12/16/09