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Chernyshov PV - The authors' results support the importance of CD28/B7 costimulation in AD children and the relation of CD28 with Th1 and Th2 cytokines. However, results do not confirm the hypothesis about the preferential role of B7-2 in Th2 activation and IgE synthesis. It could raise a question about B7-2 blockade efficacy in AD children.

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