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Physiology of normal growth
Paediatrics and Child Health, 05/06/09
Wei C et al. - Human linear growth starts from fertilisation and progresses through prenatal, infantile, early childhood and adolescent phases to be completed by fusion of the epiphyseal growth plates. After the rapid growth of foetal life, a marked deceleration follows in the first 3 years of postnatal life, which then leads to a slowly decelerating childhood component and finally a sigmoid-shaped pubertal phase. A thorough understanding of the normal pattern of human growth and the factors affecting this process is necessary for clinicians to evaluate patients referred with possible growth disorders and to identify those who require further medical input.
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