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Doss N et al. - Tacrolimus 0·1% ointment has superior efficacy to fluticasone 0·005% ointment for twice-daily treatment of adults with moderate to severe facial AD in whom conventional therapy was inadequately effective or not tolerated. Tacrolimus 0·1% ointment is a safe and effective second-line treatment for the control of moderate to severe AD of the face.

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