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Influence of anesthesia on immune responses and its effect on vaccination in children: review of evidence
Paediatric Anaesthesia, 05/17/07
Siebert J. N., et al. - We conclude that the immunomodulatory influence of anesthesia during elective surgery is both minor and transient (around 48h) and that the current evidence does not provide any contraindication to the immunization of healthy children scheduled for elective surgery. However, respecting a minimal delay of 2days (inactivated vaccines) or 14-21days (live attenuated viral vaccines) between immunization and anesthesia may be useful to avoid the risk of misinterpretation of vaccine-driven adverse events as postoperative complications
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