Interferon-Gamma Release Assay Improves the Diagnosis of Tuberculosis in Children Bianchi L et al. - The good agreement between positive IGRA and active TB disease suggests a good sensitivity of IGRA. Discrepancies between IGRA and TST can be a result of higher specificity of IGRA that is not influenced by previous BCG vaccination. IGRA may be more sensitive in children younger than 48 months. [more...]