Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Use of Antiemetic Agents in Acute Gastroenteritis 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesNonhealing painless ulcer on the sole
The Clinical Advisor, 12/16/09
Sonabend ML et al. – A Hispanic man, age 49, reported a three–year history of an enlarging painless ulcer on the plantar surface of his right foot. The ulcer began as a small fleshy bump that had opened and burst several times while continuing to grow. Occasionally, the lesion drained clear liquid, but it never became red, hot, or tender. Other than hypertension, the patient had no past medical history, no surgical history, and no history of trauma to the area. He was not taking any medications. Sensation in his foot was normal...The ulcer was an amelanotic acral melanoma. There are four main melanoma subtypes: superficial spreading (the most common), nodular, lentigo maligna, and acral lentiginous. Excision with margins of 5 mm for in situ melanoma to 2 cm for melanomas at least 2 mm deep is standard. Adjuvant chemotherapy for advanced disease requires referral to an oncologist. On biopsy, this patient's melanoma had a high mitotic rate and Breslow depth close to 4 mm. He was referred first to general surgery for wide excision and sentinel lymph–node biopsy, and then to oncology to be worked up for possible metastatic disease and need for adjuvant chemotherapy.
Related Articles
Pharmacotherapy of regional melanoma therapy
Expert Opinion in Pharmacotherapy, 12/14/09
Relevance Score: 46%
Functional implication of Netrin expression in malignant melanoma
Cellular Oncology, 12/08/09
Relevance Score: 46%
Dormancy of metastatic melanoma
Pigment Cell & Melanoma Research, 11/11/09
Relevance Score: 46%
ADAM10 Is Upregulated in Melanoma Metastasis Compared with Primary Melanoma
Journal of Investigative Dermatology, 11/03/09
Relevance Score: 46%
Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression
Modern Pathology, 11/11/09
Relevance Score: 45%
Today in Dermatology...keeping you current
Receive free subspecialty "5-minute updates" via email
Phototherapy with ultraviolet radiation: a study of hormone parameters and psychological effects
Journal of the European Academy of Dermatology and Venereology, 03/18/10
Control of negative emotions and its implication for illness perception among psoriasis and vitiligo patients
Journal of the European Academy of Dermatology and Venereology, 03/18/10
Growth rate of human fingernails and toenails in healthy American young adults
Journal of the European Academy of Dermatology and Venereology, 03/18/10
Today in Family Medicine...keeping you current
Receive free subspecialty "5-minute updates" via email
Pegloticase for chronic gout
Cochrane Reviews, 03/18/10
Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period
Cochrane Reviews, 03/18/10
Glucocorticoids for the treatment of anaphylaxis
Cochrane Reviews, 03/18/10
Today in Hematology/Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Pharmacological treatment of depression in patients with a primary brain tumour
Cochrane Reviews, 03/18/10
Angiogenesis-inhibitors for metastatic thyroid cancer
Cochrane Reviews, 03/18/10
Assessment and classification of cancer breakthrough pain: A systematic literature review
Pain, 03/18/10
Article Search
Sponsor
Sponsor