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Absence of Donor-Specific Anti-HLA Antibodies After ABO-Incompatible Heart Transplantation in Infancy: Altered Immunity or Age
American Journal of Transplantation, 12/01/09
Urschel S et al. – DSAs were absent in ABO–incompatible recipients and class II antibodies were significantly less frequent than in children with ABO–compatible transplants. This difference was present also when comparing only children transplanted below 2 years of age. Therefore, tolerance toward the donor blood group appears to be associated with an altered response to HLA beyond age–related effects.
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