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Apovian CM – The fat cell as an endocrine organ, in addition to contributions from the gut and pancreas, has helped us to understand the origins of this neuroendocrine regulation as a survival advantage in human ancestry, with obesogenic ramifications in today's toxic food environment. Suggestions for the reversal of the obesity epidemic were offered, including public health campaigns, community and medical programs, and industry–supported change in our food supply, eating patterns, and lifestyle. Community–structured programs for exercise and work–related physical activity could also engage a healthier lifestyle into the typical day for the average American as well as for individuals in other countries.


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