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Cardiovascular disease-related genes and regulation by diet
Current Atherosclerosis Reports, 11/17/09
Heuvel JPV et al. – This article reviews the evidence that specific receptors exist for fatty acids or their metabolites that are able to regulate gene expression and coordinately affect metabolic or signaling pathways associated with CVD. Four nuclear receptor subfamilies that respond to dietary and endogenous ligands and have implications for CVD are emphasized in this article: peroxisome proliferator–activated receptors, retinoid X receptors, liver X receptors, and the farnesoid X receptor.
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