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111In-labeled KCCYSL peptide as an imaging probe for ErbB-2-expressing ovarian carcinomas
Journal of Labelled Compounds and Radiopharmaceuticals, 11/05/09
Deutscher SL et al. – Blocking studies with non–radiolabeled counterpart indicated a partial inhibition (41%) (P=0.04) in tumor uptake of 111In–DOTA–GSG–KCCYSL. In vivo tumor uptake of 111In–DOTA–GSG–KCCYSL was clearly evident through SPECT/CT images after 2 h post injection. These studies suggest the potential of this peptide as a radiopharmaceutical for imaging of ErbB–2–expressing ovarian tumors.
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