PA Medical News about acute myelogenous leukaemia

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Voriconazole serum concentrations in prophylactically treated acute myelogenous leukaemia patients
Mycoses, 11/09/09

Cornely OA et al. – Among possible or probable treatment–related adverse events, elevated liver function tests were the most frequent. Five of six patients developed fever during neutropenia, but none of them developed pulmonary infiltrates or other signs of invasive fungal infection while on voriconazole prophylaxis. Future investigations might aim at identifying drug level thresholds that allow for minimum toxicity and optimum efficacy of antifungal prophylaxis.

Incidence and reasons for late failure after allogeneic haematopoietic cell transplantation following BuCy2 in acute myeloid leukaemia
British Journal of Haematology, 10/16/09 Relevance Score: 67%

Folate related gene polymorphisms and susceptibility to develop childhood acute lymphoblastic leukaemia
British Journal of Haematology, 10/05/09 Relevance Score: 67%

Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993
British Journal of Haematology, 11/04/09 Relevance Score: 66%

Arsthinol nanosuspensions: pharmacokinetics and anti-leukaemic activity on NB4 promyelocytic leukaemia cells
Journal of Pharmacy and Pharmacology, 10/07/09 Relevance Score: 66%

New insights in the management of elderly patients with acute myeloid leukemia
Current Opinion in Oncology, 10/13/09 Relevance Score: 65%