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Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/09/09
Favia G et al. – ONJ is a harmful side effect of bisphosphonate therapies. Clinicians must be aware of this entity, inform patients of the risks related to dental surgery, and possibly undertake adequate preventive measures.
Methods- Over 4 year period, total of 102 bisphosphonate-treated patients affected by ONJ identified
- 24 patients underwent bisphosphonate therapy for non-neoplastic disease and profile analyzed
- In study cohort, bisphosphonates administered mainly for postmenopausal osteoporosis (20/24 patients, 83.3%)
- Duration of therapy until presentation of ONJ ranging from 11 to 40 months
- Most common triggering event dentoalveolar surgery
- All patients nonsmokers
- 6 manifested multiple ONJ lesions
- 3 had possible comorbidities
- Surgical debridement performed in 19 patients for total of 22 lesions, which were individually considered in followup
- Latter showed complete remission of ONJ in 21/22 lesions
Today in Bone Metabolism...keeping you current
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Evaluation and management of osteoporosis and fragility fractures in the elderly
Aging Health, 11/23/09
Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation
Journal of Bone and Mineral Metabolism, 11/23/09
High pressure may inhibit periprosthetic osteogenesis
Journal of Bone and Mineral Metabolism, 11/23/09
Today in Clinical Pharmacology...keeping you current
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Effect of Chronic Sildenafil Treatment on Penile Endothelial Function: A Randomized, Double-Blind, Placebo Controlled Study
The Journal of Urology, 11/23/09
A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/23/09
Evidence for the Importance of Adiponectin in the Cardioprotective Effects of Pioglitazone
Hypertension, 11/23/09
Today in Orthopedic/Physical Med...keeping you current
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Evaluation and management of osteoporosis and fragility fractures in the elderly
Aging Health, 11/23/09
How do we define the condition ‘recurrent low back pain’? A systematic review
European Spine Journal, 11/23/09
Case–control study of knee osteoarthritis and lifestyle factors considering their interaction with physical workload
International Archives of Occupational & Environmental Health, 11/23/09
Today in Clinical Pharmacology...keeping you current
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A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/23/09
Long-Term Risk of Adverse Outcomes and New Malignancies in Patients Treated With Oral Sirolimus for Prevention of Restenosis
JACC - Journal of the American College of Cardiology: Cardiovascular Interventions, 11/23/09
Enoxaparin Versus Unfractionated Heparin in Elective Percutaneous Coronary Intervention
JACC - Journal of the American College of Cardiology: Cardiovascular Interventions, 11/23/09
Today in Rheumatology...keeping you current
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Increased Prevalence of Metabolic Syndrome in Individuals with Osteoarthritis: An Analysis of NHANES III Data
Postgraduate Medicine, 11/23/09
A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/23/09
Effect of biomagnetic therapy versus physiotherapy for treatment of knee osteoarthritis: A randomized controlled trial
Journal of Rehabilitation Medicine, 11/20/09
Today in Bone Metabolism...keeping you current
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Evaluation and management of osteoporosis and fragility fractures in the elderly
Aging Health, 11/23/09
Increased Dickkopf-1 expression accelerates bone cell apoptosis in femoral head osteonecrosis
Bone , 11/23/09
Serum TSH values and risk of vertebral fractures in euthyroid post-menopausal women with low bone mineral density
Bone , 11/20/09
Today in Bone Metabolism...keeping you current
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Evaluation and management of osteoporosis and fragility fractures in the elderly
Aging Health, 11/23/09
Serum TSH values and risk of vertebral fractures in euthyroid post-menopausal women with low bone mineral density
Bone , 11/20/09
Today in Clinical Pharmacology...keeping you current
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A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/23/09
Effect of Sildenafil on digital ulcers in systemic sclerosis - analysis from a single centre pilot study
Annals of Rheumatic Diseases, 11/23/09
Update in treatment options for psoriatic arthritis
Expert Review of Clinical Immunology, 11/23/09
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