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The safety and efficacy of liraglutide with or without oral antidiabetic drug therapy in type 2 diabetes: an overview of the LEAD 1–5 studies
Diabetes, Obesity and Metabolism, 11/06/09
Blonde L et al. – Liraglutide is a new glucagon–like peptide–1 (GLP–1) receptor agonist and a true GLP–1 analogue. After successful phase 2 studies, liraglutide was assessed in a series of phase 3 trials. Liraglutide was associated with a low risk of hypoglycaemia and was generally well tolerated. The majority of adverse effects were gastrointestinal, the most frequent of which was nausea.
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