Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Use of Antiemetic Agents in Acute Gastroenteritis 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesBimatoprost - a review
Expert Opinion in Pharmacotherapy, 11/05/09
Patil JA et al. – Bimatoprost is a synthetic prostamide analog that is efficacious in the treatment of open–angle glaucoma, ocular hypertension and other forms of glaucoma. It reduces intraocular pressure (IOP) by increasing uveoscleral and trabecular outflow. When used as a 0.03% topical preparation once daily, it demonstrates sustained lowering of IOP of 7 – 8 mmHg over a 24–h period. The drug has been found to be more effective than timolol. In some studies it has shown greater ability to lower IOP when compared with other prostaglandin analogs; whereas in others all three clinically used prostaglandin analogs were found to be equally effective. It shows good IOP reduction when used in combination with other glaucoma medications. A common side effect includes mild conjunctival hyperemia, which is generally reversible. Other side effects include periorbital pigmentation, discomfort, ocular surface hyperemia and skin changes. Pharmacoeconomic data indicate that bimatoprost is cost effective in the treatment of open–angle glaucoma.
Related Articles
Update and commentary on the pro-drug bimatoprost and a putative prostamide receptor
Expert Review of Ophthalmology, 10/21/09
Relevance Score: 89%
Bilateral Deepening of Upper Lid Sulcus From Topical Bimatoprost Therapy
Journal of Ocular Pharmacology and Therapeutics, 11/04/09
Relevance Score: 88%
A Comparison of Bimatoprost 0.03% Versus the Fixed-Combination of Latanotoprost 0.005% and Timolol 0.5% in Adult Patients With Elevated Intraocular Pressure: An Eight-Week, Randomized, Open-Label Trial
Journal of Ocular Pharmacology and Therapeutics, 11/09/09
Relevance Score: 83%
Today in Clinical Pharmacology...keeping you current
Receive free subspecialty "5-minute updates" via email
Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome
Diabetes Care, 11/25/09
Low-Density Lipoprotein Cholesterol Reduction and Goal Achievement With Ezetimibe/Simvastatin Versus Atorvastatin or Rosuvastatin in Patients With Diabetes, Metabolic Syndrome, or Neither Disease, Stratified By National Cholesterol Education Program Risk Category
Metabolic Syndrome and Related Disorders, 11/25/09
Proton Pump Inhibitors and Pain
Pain Physician, 11/25/09
Today in Ophthalmology...keeping you current
Receive free subspecialty "5-minute updates" via email
A 1-Year Retrospective Review of Ranibizumab for Naive Nonsubfoveal Choroidal Neovascularization Secondary To Age-Related Macular Degeneration
Retina, 11/25/09
Sponsor
Article Search
Sponsor
Sponsor